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Comparative Study
. 2002 Sep;14(6):416-20.
doi: 10.1016/s0952-8180(02)00390-2.

Orthotopic liver transplant patients require less postoperative morphine than do patients undergoing hepatic resection

Eugene W Moretti  1 , Kerri M Robertson, J E Tuttle-Newhall, Pierre-Alain Clavien, Tong-Joo Gan
Affiliations
Comparative Study

Orthotopic liver transplant patients require less postoperative morphine than do patients undergoing hepatic resection

Eugene W Moretti et al. J Clin Anesth. 2002 Sep.

Abstract

Study objective: To compare postoperative morphine use, analgesic efficacy, and side effect profiles in patients following orthotopic liver transplantation (OLTx) and liver resection (LR).

Design: Retrospective study.

Setting: Liver transplant and liver resection surgery at a university hospital.

Patients: 25 ASA physical status I, II, III, and IV patients undergoing OLTx or liver resection.

Measurements and main results: Morphine use was significantly decreased in the OLTx patients at 6,12, 24, 48, and 72 hours following commencement of patient-controlled analgesia. After commencement of patient-controlled analgesia, pain scores were significantly reduced in the OLTx group compared with those in the liver resection group at 6 and 12 hours.

Conclusions: Orthotopic liver transplant patients experienced less pain and used less morphine postoperatively than did liver resection patients.

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