The effect of canavanine on the capsid protein of Sindbis virus
- PMID: 1239648
The effect of canavanine on the capsid protein of Sindbis virus
Abstract
In the presence of the arginine analogue canavanine, Sindbis virus-infected BHK 21 cells synthesize a capsid protein of somewhat larger molecular weight than that of controls. This protein can also be seen in short pulse-labelled cells, and probably represents a precursor of the normal capsid protein. In our experiments canavanine had no effect on the viral envelope proteins, and the canavanine containing capsid protein formed nucleocapsids and virus particles as well as normal capsid protein does.
Similar articles
-
Effect of cycloheximide on viral precursor protein B in Sindbis virus-infected BHK cells.Med Biol. 1975 Oct;53(5):368-71. Med Biol. 1975. PMID: 1239649
-
Formation of Sindbis virus capsid protein in mammalian cell-free extracts programmed with viral messenger RNA.Proc Natl Acad Sci U S A. 1974 May;71(5):1843-7. doi: 10.1073/pnas.71.5.1843. Proc Natl Acad Sci U S A. 1974. PMID: 4525296 Free PMC article.
-
Large-molecular-weight precursors of sindbis virus proteins.J Virol. 1973 Jun;11(6):1013-6. doi: 10.1128/JVI.11.6.1013-1016.1973. J Virol. 1973. PMID: 4736531 Free PMC article.
-
Head length control in T4 bacteriophage morphogenesis: effect of canavanine on assembly.Bacteriol Rev. 1976 Jun;40(2):314-59. doi: 10.1128/br.40.2.314-359.1976. Bacteriol Rev. 1976. PMID: 786254 Free PMC article. Review. No abstract available.
-
The biological effects and mode of action of L-canavanine, a structural analogue of L-arginine.Q Rev Biol. 1977 Jun;52(2):155-78. doi: 10.1086/409853. Q Rev Biol. 1977. PMID: 331385 Review.