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Multicenter Study
. 2002 Nov;73(5):495-9.
doi: 10.1136/jnnp.73.5.495.

Chronic alcohol use and first symptomatic epileptic seizures

M Leone  1 , C Tonini, G Bogliun, F Monaco, R Mutani, E Bottacchi, P Gambaro, E Rocci, T Tassinari, C Cavestro, E Beghi
Affiliations
Multicenter Study

Chronic alcohol use and first symptomatic epileptic seizures

M Leone et al. J Neurol Neurosurg Psychiatry. 2002 Nov.

Abstract

Objective: To establish whether chronic alcoholism and alcohol consumption are risk factors for developing a first symptomatic epileptic seizure.

Methods: Multicentre case-control study of 293 patients (160 men, 133 women) with a first seizure symptomatic (either acute or remote) of head trauma, stroke, or brain tumour, matched to 444 hospital controls for centre, sex, age (+/-5 years), and underlying pathology.

Results: The risk of first seizure in alcoholics was no higher than in non-alcoholics for men (odds ratio 1.2, 95% confidence interval 0.4 to 3.2) or women (1.5, 0.1 to 54.4). The odds ratio (both sexes) was 1.2 (0.8 to 1.7) for an average intake of absolute alcohol of 1-25 g/day, 0.9 (0.5 to 1.5) for 26-50 g/day, 1.6 (0.8 to 3.0) for 51-100 g/day, and 1.4 (0.5 to 3.5) for >100 g/day.

Conclusions: We found no evidence of an association between alcohol use or alcoholism and a first symptomatic seizure.

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References

    1. Eur J Neurol. 1999 Nov;6(6):697-703 - PubMed
    1. MMW Munch Med Wochenschr. 1977 Oct 7;119(40):1275-82 - PubMed
    1. Stroke. 1980 Mar-Apr;11(2):162-5 - PubMed
    1. Epilepsia. 1980 Oct;21(5):459-66 - PubMed
    1. Lancet. 1982 Feb 6;1(8267):325-8 - PubMed

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