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Review
. 2002 Sep-Oct;47(5):833-41.

[Biophysical and medical and biological aspects of use of polyene antibiotics in combination with dimethylsulfoxide]

[Article in Russian]
V Kh Ibragimova  1 , D I Aliev, I N Alieva
Affiliations
  • PMID: 12397953
Review

[Biophysical and medical and biological aspects of use of polyene antibiotics in combination with dimethylsulfoxide]

[Article in Russian]
V Kh Ibragimova et al. Biofizika. 2002 Sep-Oct.

Abstract

Modern conceptions of the physicochemical properties of dimethylsulfoxide and polyene antibiotics are reviewed. The results of investigations of independent and mutual effects of polyene antibiotics and dimethylsulfoxide on membrane permeability were analysed. The own experimental data of radioprotective and antitumour action of complex dimethylsulfoxide-polyene antibiotics are presented, and the perspectives of their use in medicine are described.

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