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Review
. 2002 Oct 25;298(5594):770-6.
doi: 10.1126/science.1075510.

The developing synapse: construction and modulation of synaptic structures and circuits

Susana Cohen-Cory  1
Affiliations
Review

The developing synapse: construction and modulation of synaptic structures and circuits

Susana Cohen-Cory. Science. .

Abstract

Synapse formation and stabilization in the vertebrate central nervous system is a dynamic process, requiring bi-directional communication between pre- and postsynaptic partners. Numerous mechanisms coordinate where and when synapses are made in the developing brain. This review discusses cellular and activity-dependent mechanisms that control the development of synaptic connectivity.

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