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Review
. 2002 Oct;60(10 Pt 2):S15-9; discussion S68-84, 85-7.
doi: 10.1301/002966402320634788.

The role of leptin in the control of body weight

Rudolph L Leibel  1
Affiliations
Review

The role of leptin in the control of body weight

Rudolph L Leibel. Nutr Rev. 2002 Oct.

Abstract

Physiologic responses to high and low leptin concentrations are strikingly asymmetrical. High concentrations often produce minimal effects, whereas low concentrations provoke strong counterregulatory responses. A model and rationale for the physiology is presented.

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