Treatment of mood disorders
- PMID: 12403988
- DOI: 10.1038/nn943
Treatment of mood disorders
Abstract
Depression is a leading cause of morbidity and mortality, and its treatment includes a high percentage of the medications prescribed by physicians. Available antidepressant drugs are safe and effective, but less than half of all patients attain complete remission after therapy with a single antidepressant. Others exhibit partial, refractory or intolerant responses to treatment, emphasizing the need to discover new antidepressants. The mechanisms of action of available medications are directing the field toward new research avenues. This review highlights those areas we believe will influence the field and soon lead to better treatment.
Comment in
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Financial disclosure for review authors.Nat Neurosci. 2003 Oct;6(10):997. doi: 10.1038/nn1003-997. Nat Neurosci. 2003. PMID: 14513027 No abstract available.
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Editorial policies on financial disclosure.Nat Neurosci. 2003 Oct;6(10):999-1000; author reply 1000-1. doi: 10.1038/nn1003-999. Nat Neurosci. 2003. PMID: 14513028 No abstract available.
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Editorial policies on financial disclosure.Nat Neurosci. 2003 Oct;6(10):1001. doi: 10.1038/nn1003-1001. Nat Neurosci. 2003. PMID: 14513030 No abstract available.
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