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. 2000 Aug;15(6):397-415.
doi: 10.1002/1099-1077(200008)15:6<397::AID-HUP212>3.0.CO;2-L.

A review of the role of serotonin receptors in psychiatric disorders

Marie Naughton  1 , Jane B. Mulrooney, Brian E. Leonard
Affiliations

A review of the role of serotonin receptors in psychiatric disorders

Marie Naughton et al. Hum Psychopharmacol. 2000 Aug.

Abstract

Serotonin (5-hydroxytryptamine, 5-HT) mediates a wide variety of physiological functions by activating multiple receptors, and abnormalities of these receptor systems has been implicated in many psychiatric disorders including anxiety, depression, psychosis, migraine, disorders of sexual functioning, sleep, cognition, and feeding. Many of the currently used treatments for these disorders act by affecting the serotonergic system. Observation of serotonin receptor alterations, before and following effective treatments, may yield important insights into the aetiology of these psychiatric disorders and may ultimately lead to more selective and effective therapies. Copyright 2000 John Wiley & Sons, Ltd.

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