Paget's disease of bone: presentation, extent and response to bisphosphonates
- PMID: 12405502
Paget's disease of bone: presentation, extent and response to bisphosphonates
Abstract
According to a radiograph survey in 1982, Paget's disease of bone is common in Ireland but, to date, there have been no clinical reports. In a survey of 24 patients with Paget's disease of bone, we found monostotic disease in 8 and polyostotic disease in 16. Complications were common including deformity (21%), fracture (17%) and deafness (8%). Bisphosphonate therapy induced a remission in 22 patients.
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