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. 1975 Apr;148(4):1018-24.
doi: 10.3181/00379727-148-38680.

Neuraminidase treated homologous IgG and immune deposit rental disease in inbred rats

W R Griswold, J R McIntosh, R Weil 3rd, R M McIntosh

Neuraminidase treated homologous IgG and immune deposit rental disease in inbred rats

W R Griswold et al. Proc Soc Exp Biol Med. 1975 Apr.

Abstract

Immune deposit renal disease followed intravenous or intraperitoneal injections of neuraminidase treated homologous IgG or neuraminidase alone. No alterations were associated with several groups of controls. This preliminary study suggests that one mechanism by which microogranisms may be involved in the development of immune renal disease is by chemical alteration of immunoglobulin.

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