Duplicating dangerously: linking centrosome duplication and aneuploidy
- PMID: 12408813
- DOI: 10.1016/s1097-2765(02)00654-8
Duplicating dangerously: linking centrosome duplication and aneuploidy
Abstract
Centrosomes are far more fascinating than the first explorers of this organelle a century ago could ever have imagined. Recent evidence indicates that deregulation of centrosome duplication affects centrosome number and promotes aneuploidy, features characteristic of human tumors.
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