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Review
. 2002 Sep;10(3):439-40.
doi: 10.1016/s1097-2765(02)00654-8.

Duplicating dangerously: linking centrosome duplication and aneuploidy

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Free article
Review

Duplicating dangerously: linking centrosome duplication and aneuploidy

Stephen Doxsey. Mol Cell. 2002 Sep.
Free article

Abstract

Centrosomes are far more fascinating than the first explorers of this organelle a century ago could ever have imagined. Recent evidence indicates that deregulation of centrosome duplication affects centrosome number and promotes aneuploidy, features characteristic of human tumors.

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