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. 2002 Oct 18;111(2):159-62.
doi: 10.1016/s0092-8674(02)01039-5.

A chromosome RNAissance

Abby F Dernburg  1 , Gary H Karpen
Affiliations
Free article

A chromosome RNAissance

Abby F Dernburg et al. Cell. .
Free article

Abstract

In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.

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