Comment on

• Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

  Hock C, Konietzko U, Papassotiropoulos A, Wollmer A, Streffer J, von Rotz RC, Davey G, Moritz E, Nitsch RM. Hock C, et al. Nat Med. 2002 Nov;8(11):1270-5. doi: 10.1038/nm783. Epub 2002 Oct 15. Nat Med. 2002. PMID: 12379846 Clinical Trial.
• Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

  McLaurin J, Cecal R, Kierstead ME, Tian X, Phinney AL, Manea M, French JE, Lambermon MH, Darabie AA, Brown ME, Janus C, Chishti MA, Horne P, Westaway D, Fraser PE, Mount HT, Przybylski M, St George-Hyslop P. McLaurin J, et al. Nat Med. 2002 Nov;8(11):1263-9. doi: 10.1038/nm790. Epub 2002 Oct 15. Nat Med. 2002. PMID: 12379850