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. 2002 Nov;29(11):2407-9.

Active ingredient consistency of commercially available glucosamine sulfate products

Anthony S Russell  1 , Ali Aghazadeh-Habashi, Fakhreddin Jamali
Affiliations
  • PMID: 12415601

Active ingredient consistency of commercially available glucosamine sulfate products

Anthony S Russell et al. J Rheumatol. 2002 Nov.

Abstract

Objective: To assess the content of active ingredient in over-the-counter (OTC) glucosamine sulfate (GLS) preparations.

Methods: We analyzed in a coded, blind manner 14 commercially available capsules or tablets of GLS, plus one herbal mixture as a control. We used a high performance liquid chromatography system as described.

Results: The amount of free base varied from 41 to 108% of the mg content stated on the label; the amount of glucosamine varied from 59 to 138% even when expressed as sulfate.

Conclusion: If GLS is used as a therapeutic agent, it is important that the products conform to a standard in their description. The content is probably best expressed in terms of free base.

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