Two pathways to NF-kappaB
- PMID: 12419209
- DOI: 10.1016/s1097-2765(02)00697-4
Two pathways to NF-kappaB
Abstract
NF-kappaB is a transcription factor that is critical for innate and adaptive immunity. Recently, a noncanonical pathway for NF-kappaB activation has emerged. Four recent papers provide physiological roles for this pathway and expand our understanding of lymphoid development and organogenesis with potential applications in the treatment of autoimmune disease.
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