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. 2002 Dec 2;12(23):3379-82.
doi: 10.1016/s0960-894x(02)00761-8.

Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine

Kuo Long Yu  1 , Albert F Torri, Guangxiang Luo, Christopher Cianci, Katharine Grant-Young, Stephanie Danetz, Lawrence Tiley, Mark Krystal, Nicholas A Meanwell
Affiliations

Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine

Kuo Long Yu et al. Bioorg Med Chem Lett. .

Abstract

The anti-influenza activity of a series of thiobenzamide fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine is profiled. Axial disposition of the thioamide moiety is essential for potent influenza inhibitory activity.

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