Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia
- PMID: 12423093
- DOI: 10.1021/ol0268337
Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia
Abstract
Extracts of the marine sponge Caminus sphaeroconia showed potent activity in a screen for bacterial type III secretion inhibitors. Bioassay guided fractionation of the extract led to the isolation of the novel antimicrobial glycolipid caminoside A (1). The structure of caminoside A was elucidated by analysis of spectroscopic data and chemical degradation.[structure: see text]
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