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. 2002 Nov 14;4(23):4089-92.
doi: 10.1021/ol0268337.

Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia

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Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia

Roger G Linington et al. Org Lett. .

Abstract

Extracts of the marine sponge Caminus sphaeroconia showed potent activity in a screen for bacterial type III secretion inhibitors. Bioassay guided fractionation of the extract led to the isolation of the novel antimicrobial glycolipid caminoside A (1). The structure of caminoside A was elucidated by analysis of spectroscopic data and chemical degradation.[structure: see text]

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