[MASCA-model of the biochemical-pharmacological drug research. Part 3: Structure-activity relationships and KANORA (author's transl)]
- PMID: 1242657
[MASCA-model of the biochemical-pharmacological drug research. Part 3: Structure-activity relationships and KANORA (author's transl)]
Abstract
The KANORA (multivariate regression and correlation analysis) leads to a combination with the multivariate structure-activity analysis which encloses the time-, dose-response and biological screening analysis. Drug-receptor interactions can be considered in connection with structure-action relationship. The importance of the analysis of "nonsense"-correlations (by using the partial correlation) and the model II of regression analysis is demonstrated.