Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients
- PMID: 12427897
- DOI: 10.1212/01.wnl.0000032756.14298.18
Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients
Abstract
A series of 24 consecutive PD patients were prospectively studied prior to and within 6 months postoperatively for mood, motor, and cognitive status to investigate the effects on mood of subthalamic deep brain stimulation (DBS) in PD. In six patients (25%), mood state worsened significantly, and three were transiently suicidal despite clear motor improvement. Caregivers and patients should be educated about the potential impact of this neurosurgical procedure on mood.
Comment in
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Penfield revisited? Understanding and modifying behavior by deep brain stimulation for PD.Neurology. 2002 Nov 12;59(9):1298-9. doi: 10.1212/wnl.59.9.1298. Neurology. 2002. PMID: 12427872 Review. No abstract available.
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