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. 2002 Nov 12;59(9):1427-9.
doi: 10.1212/01.wnl.0000032756.14298.18.

Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients

A Berney  1 , F Vingerhoets, A Perrin, P Guex, J-G Villemure, P R Burkhard, C Benkelfat, J Ghika
Affiliations

Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients

A Berney et al. Neurology. .

Abstract

A series of 24 consecutive PD patients were prospectively studied prior to and within 6 months postoperatively for mood, motor, and cognitive status to investigate the effects on mood of subthalamic deep brain stimulation (DBS) in PD. In six patients (25%), mood state worsened significantly, and three were transiently suicidal despite clear motor improvement. Caregivers and patients should be educated about the potential impact of this neurosurgical procedure on mood.

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