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Review
. 2002 Oct;19(5):542-80.
doi: 10.1039/b103920m.

Modification of post-PKS tailoring steps through combinatorial biosynthesis

Uwe Rix  1 , Carsten Fischer, Lily L Remsing, Jürgen Rohr
Affiliations
Review

Modification of post-PKS tailoring steps through combinatorial biosynthesis

Uwe Rix et al. Nat Prod Rep. 2002 Oct.

Abstract

This review covers the highlights of combinatorial biosynthesis applied on post-polyketide synthase modifying enzymes, such as oxygenases. ketoreductases, glycosyl- and methyltransferases, acyltransferases, halogenases, cyclases and aminotransferases Since this is the first review on this topic, it covers literature from 1985 to 2002, and 248 references are given.

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