Review
doi: 10.1016/s1534-5807(02)00328-3.
Survival signaling goes BAD
Affiliations
- PMID: 12431365
- DOI: 10.1016/s1534-5807(02)00328-3
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Review
Survival signaling goes BAD
Dev Cell.
2002 Nov.
Free article
Abstract
Work published in this issue of Developmental Cell demonstrates, in vivo, that the proapoptotic gene BAD provides a genetic link between the cell death machinery and survival signaling. This work has implications for development, tissue homeostasis, and tumorigenesis.
Comment on
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Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis.Dev Cell. 2002 Nov;3(5):631-43. doi: 10.1016/s1534-5807(02)00326-x. Dev Cell. 2002. PMID: 12431371
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