Clostridium septicum infection associated with perforation of colon diverticulum

Abstract

Non-traumatic or spontaneous gas gangrene by Clostridium septicum is a rare infection in humans, characterised by extensive destruction of muscle tissue, a mortality rate of 100% if left untreated (1), and often associated with haematological or colorectal diseases. An associated malignancy was found in 80% of patients with Clostridium septicum infection: 34% had a colorectal carcinoma and 40% had a haematological malignancy (2); the infection usually lies in an often-ulcerated intestinal lesion (3). We report here a case of spontaneous gas gangrene by Clostridium septicum in the right thigh due to perforation of a diverticulum in the sigmoid colon.