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Comparative Study
. 2002 Nov 9;119(16):610-2.
doi: 10.1016/s0025-7753(02)73514-8.

[Intravenous cyclosporine A in the treatment of refractory Crohn's disease]

[Article in Spanish]
Esther García-Planella  1 , Eugeni Domènech, Eduard Cabré, M Isabel Bernal, Miquel Angel Gassull
Affiliations
Comparative Study

[Intravenous cyclosporine A in the treatment of refractory Crohn's disease]

[Article in Spanish]
Esther García-Planella et al. Med Clin (Barc). .

Abstract

Background: Intravenous cyclosporine (iv CyA) is efficient in ulcerative colitis, but data are scarce in Crohn's disease (CD).

Patients and method: Patients with CD refractory to standard therapy who were treated with iv CyA.

Results: All patients with steroid-refractory disease achieved a complete response. In perianal disease, a complete response was attained in 3 out of 16 patients, while 9 showed a partial response. Only 1 out of 8 patients with enteric fistulae showed a complete response and a further one had a partial response.

Conclusions: Intravenous CyA seems to be useful in steroid-refractory CD but not in fistulizing CD.

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