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Review
. 2002 Nov 15;91(10):888-98.
doi: 10.1161/01.res.0000041680.43270.f8.

Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy

Mark A Sussman  1 , Andrew McCulloch, Thomas K Borg
Affiliations
Free article
Review

Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy

Mark A Sussman et al. Circ Res. .
Free article

Abstract

Biomechanical signaling is a complex interaction of both intracellular and extracellular components. Both passive and active components are involved in the extracellular environment to signal through specific receptors to multiple signaling pathways. This review provides an overview of extracellular matrix, specific receptors, and signaling pathways for biomechanical stimulation in cardiac hypertrophy.

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