Oral cancer treatment: developments in chemotherapy and beyond
- PMID: 12434279
- PMCID: PMC2364332
- DOI: 10.1038/sj.bjc.6600591
Oral cancer treatment: developments in chemotherapy and beyond
Abstract
Oncology is one of the few areas of medicine where most patients are treated intravenously rather than receiving oral drugs. Recently, several oral anti-cancer drugs have been approved and there are many more in development. Oral chemotherapy is attractive because of its convenience and ease of administration, particularly in the palliative setting. With an increasing number of oral agents emerging, we can expect to see a rapid rise in the use of oral chemotherapy in years to come. This article reviews recent developments in oral chemotherapy, both of traditional cytotoxics and novel, targeted agents, from the viewpoint of patients, physicians, drug developers and health-care providers.
References
-
- BornerMMDietrichDStuppRMorantRHoneggerHWernliMHerrmannRPestalozziBCSalettiPHanselmannSMullerSBrauchliPCastiglione-GertschMGoldhirschARothAD2002Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer J Clin Oncol 20717591766 - PubMed
-
- BaselgaJ2001The EGFR as a target for anticancer therapy–focus on cetuximab Eur J Cancer 37Suppl 4S16S22 - PubMed
-
- BaselgaJHerbstRLoRussoPRischinDRansonMPlummerRRaymondEMaddoxA-MKayeSBKieback DGHarrisAOchsJ2000Continuous Administration of ZD1839 (Iressa), a Novel Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI), in Patients with Five Selected Tumor Types: Evidence of Activity and Good Tolerability Proc Am Soc Clin Oncol 19177
-
- CassidyJTwelvesCCameronDStewardWO'ByrneKJodrellDBankenLGogginTJonesDRoosBBushEWeidekammEReignerB1999Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients Cancer Chemother Pharmacol 446453460 - PubMed
-
- DeMarioMDRatainMJ1998Oral chemotherapy: rationale and future directions J Clin Oncol 16725572567 - PubMed
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