Cytogenetic studies of preinvasive lesions and invasive carcinomas' of the cervix uteri. III. Survey and interpretation of the results reported in the literature

Abstract

Summary. Cytogenetic studies were performed of 54 preinvasive carcinomas and invasive squamous cervix carcinomas altogether. The chromosome number could be determined in 9 dysplasias, 25 carcinomas in situ, 4 carcinomas in situ with micro-invasion and 16 invasive squamous carcinomas (at least clinical stage Ib). It was shown that carcinomas in situ, carcinomas in situ with microinvasion and invasive squamous carcinomas could not be differentiated from each other in principle as groups with regard to numerical chromosome deviations...