Evaluating mixed stains with contributors of different ethnic groups under the NRC-II Recommendation 4.1
- PMID: 12436457
- DOI: 10.1002/sim.1313
Evaluating mixed stains with contributors of different ethnic groups under the NRC-II Recommendation 4.1
Abstract
In countries with multiple racial or ethnic groups, it is not uncommon that contributors to a mixed stain or a DNA mixture belong to different ethnic origins. This paper derives a general formula for evaluating the likelihood ratio in such situations based on the commonly adopted Recommendation 4.1 of the U.S. Second National Research Council Report on the evaluation of DNA evidence. The restrictive Hardy-Weinberg assumption is not taken in this paper. Our formula generalizes the results of Fung and Hu for a single ethnic group, and of Weir et al. under the Hardy-Weinberg law for a single, and Fukshansky and Bär for multiple ethnic groups. The effect of different ethnic groups of contributors to the interpretation of mixtures is illustrated through the analysis of the Simpson case.
Copyright 2002 John Wiley & Sons, Ltd.
Similar articles
-
The evaluation of mixed stains from different ethnic origins: general result and common cases.Int J Legal Med. 2001 Aug;115(1):48-53. doi: 10.1007/s004140100205. Int J Legal Med. 2001. PMID: 11599769
-
Interpreting DNA mixtures.J Forensic Sci. 1997 Mar;42(2):213-22. J Forensic Sci. 1997. PMID: 9068179 Review.
-
Evaluating forensic DNA mixtures with contributors of different structured ethnic origins: a computer software.Int J Legal Med. 2003 Aug;117(4):248-9. doi: 10.1007/s00414-003-0378-3. Epub 2003 Jun 21. Int J Legal Med. 2003. PMID: 12827379
-
Interpretation of complex forensic DNA mixtures.Croat Med J. 2001 Jun;42(3):244-6. Croat Med J. 2001. PMID: 11387631 Review.
-
[Interpretation of DNA profiles for mixed stains].Fa Yi Xue Za Zhi. 2002 Aug;18(3):185-8. Fa Yi Xue Za Zhi. 2002. PMID: 12608297 Review. Chinese.
Cited by
-
Identifying individuals in a complex mixture of DNA with unknown ancestry.Stat Appl Genet Mol Biol. 2009;8(1):Article 37. doi: 10.2202/1544-6115.1469. Epub 2009 Sep 9. Stat Appl Genet Mol Biol. 2009. PMID: 19799556 Free PMC article.