[Development of highly selective reactions based on metal carbonyls and its application to synthesis of bioactive compounds]

Abstract

Alkynes react with commercially available Co2 (CO)8 to give the corresponding alkyne-Co2 (CO)6 complexes. Similarly, treatment of arenes with Cr(CO)6 produces arene-Cr (CO)3 complexes. By taking advantage of the intriguing properties of these metal carbonyl complexes, we developed some selective reactions. In this review, the following topics are discussed: (i) development of selective reactions based on alkyne-Co2 (CO)6 complexes; (ii) development of selective reactions based on arene-Cr (CO)3 complexes; and (iii) their application to syntheses of bioactive compounds.