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Review
. 2002 Dec;4(6):467-73.
doi: 10.1007/s11920-002-0075-9.

The role of ovarian hormones in preserving cognition in aging

Jeri S Janowsky  1
Affiliations
Review

The role of ovarian hormones in preserving cognition in aging

Jeri S Janowsky. Curr Psychiatry Rep. 2002 Dec.

Abstract

Hormone replacement therapy is now the standard of care for amelioration of the symptoms of menopause and prevention of osteoporosis. More recently, it has been appreciated that hormone replacement may also have beneficial effects on the brain. This review will contrast the biologic data showing that estrogen has significant neuroprotectant effects on the brain, with data from cross-sectional and epidemiologic studies of women showing that hormone replacement may have beneficial effects for cognition in aging. Together, studies suggest that the temporal pattern of hormone replacement may be critical for maintaining cognitive health in aging.

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