Spatially restricted actions of BDNF
- PMID: 12441043
- DOI: 10.1016/s0896-6273(02)01063-2
Spatially restricted actions of BDNF
Abstract
In this issue of Neuron, Zhang and Poo present evidence for localized BDNF-induced synaptic potentiation that is accompanied by spatially restricted calcium influx and requires local axonal protein synthesis. These results are consistent with a synapse-specific role for BDNF and provide a potentially novel way to think about cellular mechanisms for potentiation of neurotransmitter release.
Comment on
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Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon.Neuron. 2002 Nov 14;36(4):675-88. doi: 10.1016/s0896-6273(02)01023-1. Neuron. 2002. PMID: 12441056
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