Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2002 Nov 22;16(17):2342-4.
doi: 10.1097/00002030-200211220-00018.

Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions

Becky Schweighardt  1 , Gabriel M Ortiz, Robert M Grant, Melissa Wellons, G Diego Miralles, Leondios G Kostrikis, John A Bartlett, Douglas F Nixon
Affiliations

Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions

Becky Schweighardt et al. AIDS. .

Abstract

We report the emergence of drug-resistant viral mutations in chronically HIV-infected individual undergoing structured treatment interruptions (STI). THe protease mutations K101E and K103N were detected at the end of the second or third STI. We concluded that the repeated abrupt termination and resumption of certain antiretroviral drug regimens during STI therapy may lead to the development of drug resistance in chronically HIV-infected individuals.

PubMed Disclaimer

Publication types

LinkOut - more resources