doi: 10.1081/NCN-120014815.
Formation of 2'-deoxy-2-nitroadenosines by reaction of 2'-deoxyadenosines with copper(II) nitrate/acetic anhydride
Affiliations
- PMID: 12442960
- DOI: 10.1081/NCN-120014815
Item in Clipboard
Formation of 2'-deoxy-2-nitroadenosines by reaction of 2'-deoxyadenosines with copper(II) nitrate/acetic anhydride
Nucleosides Nucleotides Nucleic Acids.
2002 Jun-Jul.
Abstract
Nitration of 9-substituted [ethyl, (Ac)2-2'-deoxyribosyl, (Ac)3-ribosyl] N6-acetyladenine derivatives with Cu(NO3)2.3H2O/Ac2O was examined. Nitration proceeded at the 2-position, although the yield was low. Removal of the acetyl groups gave 2'-deoxy-2-nitroadenosine derivatives.
Similar articles
-
Scandium(III) trifluoromethanesulfonate catalyzed aromatic nitration with inorganic nitrates and acetic anhydride.Chem Pharm Bull (Tokyo). 2002 Aug;50(8):1060-5. doi: 10.1248/cpb.50.1060. Chem Pharm Bull (Tokyo). 2002. PMID: 12192137
-
Copper-catalyzed Perkin-acyl-Mannich reaction of acetic anhydride with pyridine: expeditious entry to unconventional piperidines.Org Lett. 2011 Oct 7;13(19):5152-5. doi: 10.1021/ol202027k. Epub 2011 Sep 6. Org Lett. 2011. PMID: 21894883
-
Synthesis of 2'-([1,2,3]triazol-1-yl)-2'-deoxyadenosines.Nucleosides Nucleotides Nucleic Acids. 2008 May;27(5):449-59. doi: 10.1080/15257770802086880. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18569784
-
Facile Cu(OTf)2-catalyzed preparation of per-O-acetylated hexopyranoses with stoichiometric acetic anhydride and sequential one-pot anomeric substitution to thioglycosides under solvent-free conditions.J Org Chem. 2003 Oct 31;68(22):8719-22. doi: 10.1021/jo030073b. J Org Chem. 2003. PMID: 14575510
-
Problems in the interpretation of nonaqueous titrations.Pharmazie. 2005 Apr;60(4):243-6. Pharmazie. 2005. PMID: 15881600 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources