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Review
. 2002 Nov 19;12(22):R776-8.
doi: 10.1016/s0960-9822(02)01291-5.

Hox proteins: sculpting body parts by activating localized cell death

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Free article
Review

Hox proteins: sculpting body parts by activating localized cell death

Claudio R Alonso. Curr Biol. .
Free article

Abstract

Hox proteins shape animal structures by eliciting different developmental programs along the anteroposterior body axis. A recent study reveals that the Drosophila Hox protein Deformed directly activates the cell-death-promoting gene reaper to maintain the boundaries between distinct head segments.

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