The final cut: how ERAP1 trims MHC ligands to size
- PMID: 12447365
- DOI: 10.1038/ni1202-1121
The final cut: how ERAP1 trims MHC ligands to size
Comment on
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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides.Nat Immunol. 2002 Dec;3(12):1169-76. doi: 10.1038/ni859. Epub 2002 Nov 18. Nat Immunol. 2002. PMID: 12436109
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The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues.Nat Immunol. 2002 Dec;3(12):1177-84. doi: 10.1038/ni860. Epub 2002 Nov 18. Nat Immunol. 2002. PMID: 12436110
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