23Na-MRI of the human heart using a 3D radial projection technique

Abstract

Sodium MRI has the potential to differentiate viable and non-viable infarcted myocardium. The accurate quantification of the total sodium content requires imaging techniques with ultra short echo times below 0.5 ms. We present a 3D-radial projection technique which allows the acquisition of ECG-triggered sodium images of the human heart with echo times of 0.4 ms. A 3D-data set of the heart of a volunteer was acquired within less than 18 min on a clinical scanner (1.5 T), achieving a SNR of 10 in the myocardium with an isotropic resolution of 10 mm. This technique provides a tool for clinical studies of ischemic heart diseases.