Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2002 Nov;71(5):1247-50; author reply 1250-1.
doi: 10.1086/344287.

Alcohol dehydrogenase and alcohol dependence: variation in genotype-associated risk between populations

John B Whitfield
Comment

Alcohol dehydrogenase and alcohol dependence: variation in genotype-associated risk between populations

John B Whitfield. Am J Hum Genet. 2002 Nov.
No abstract available

PubMed Disclaimer

Comment on

References

Electronic-Database Information

    1. Online Mendelian Inheritance in Man (OMIM), http://www.ncbi.nlm.nih.gov/Omim/ (for ADH1B [MIM 103720], alcoholism [MIM 103780], and ALDH2 [MIM 100650]

References

    1. Borras E, Coutelle C, Rosell A, Fernandez-Muixi F, Broch M, Crosas B, Hjelmqvist L, Lorenzo A, Gutierrez C (2000) Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology 31:984–989 - PubMed
    1. Bosron WF, Li TK (1986) Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 6:502–510 - PubMed
    1. Chen WJ, Loh EW, Hsu YP, Chen CC, Yu JM, Cheng AT (1996) Alcohol-metabolising genes and alcoholism among Taiwanese Han men: independent effect of ADH2, ADH3 and ALDH2. Br J Psychiatry 168:762–767 - PubMed
    1. Espinos C, Sanchez F, Ramirez C, Juan F, Najera C (1997) Polymorphism of alcohol dehydrogenase genes in alcoholic and nonalcoholic individuals from Valencia (Spain). Hereditas 126:247–253 - PubMed
    1. Frenzer A, Butler WJ, Norton ID, Wilson JS, Apte MV, Pirola RC, Ryan P, Roberts-Thomson IC (2002) Polymorphism in alcohol-metabolizing enzymes, glutathione S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and chronic pancreatitis. J Gastroenterol Hepatol 17:177–182 - PubMed

Substances

Associated data