Pancytopenia responding to treatment of hyperthyroidism: a clinical case and review of the literature
- PMID: 12452820
- DOI: 10.1046/j.1365-2257.2002.00460.x
Pancytopenia responding to treatment of hyperthyroidism: a clinical case and review of the literature
Abstract
A 46-year-old-man received high dose chemotherapy and an autologous stem-cell transplant for multiple plasmacytoma. He had a prolonged period of pancytopenia post-transplantation, which was thought to be due to a suboptimal dose of transplanted stem cells in combination with the effects of interferon therapy and an altered bone marrow microenvironment. Twenty-eight months after the transplant he was found to be hyperthyroid. Anti-thyroid therapy has led to a sustained improvement in his pancytopenia.
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