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. 2002 Nov-Dec;42(10):974-7.
doi: 10.1046/j.1526-4610.2002.02226.x.

Familial cluster headache: a series of 186 index patients

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Familial cluster headache: a series of 186 index patients

Mohammed El Amrani et al. Headache. 2002 Nov-Dec.

Abstract

Objective: To investigate the familial occurrence of cluster headache in a series of French patients fulfilling the International Headache Society diagnosis criteria.

Methods: One hundred eighty-six index patients and 624 first-degree relatives were surveyed.

Results: A positive family history of cluster headache was found in 20 index patients (10.75%) with 22 affected first-degree relatives (3.4%). In multiplex families 6 of the 68 second-degree relatives that were contacted had cluster headache.

Conclusion: No precise mode of inheritance could be drawn from the observed repartition of cases within multiplex families.

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