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. 2002 Nov;8(11):1290-3.
doi: 10.3201/eid0811.020302.

Human exposure following Mycobacterium tuberculosis infection of multiple animal species in a Metropolitan Zoo

Peter Oh  1 , Reuben Granich, Jim Scott, Ben Sun, Michael Joseph, Cynthia Stringfield, Susan Thisdell, Jothan Staley, Donna Workman-Malcolm, Lee Borenstein, Eleanor Lehnkering, Patrick Ryan, Jeanne Soukup, Annette Nitta, Jennifer Flood
Affiliations

Human exposure following Mycobacterium tuberculosis infection of multiple animal species in a Metropolitan Zoo

Peter Oh et al. Emerg Infect Dis. 2002 Nov.

Abstract

From 1997 to 2000, Mycobacterium tuberculosis was diagnosed in two Asian elephants (Elephas maximus), three Rocky Mountain goats (Oreamnos americanus), and one black rhinoceros (Diceros bicornis) in the Los Angeles Zoo. DNA fingerprint patterns suggested recent transmission. An investigation found no active cases of tuberculosis in humans; however, tuberculin skin-test conversions in humans were associated with training elephants and attending an elephant necropsy.

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Figures

Figure
Figure
IS6110 restriction fragment length polymorphism results of the six animal isolates and the Mycobacterium tuberculosis reference strain Mtb14323. Molecular weights of IS6110-containing PvuII fragments of the reference strain are approximately 17, 7.4, 7.1, 4.5, 3.6, 3.1, 2.1, 1.9, 1.7, 1.5, and 1.4 kb.
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