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. 1976 Jan;125(1):48-57.
doi: 10.1128/jb.125.1.48-57.1976.

Mutants of Saccharomycopsis lipolytica defective in lysine catabolism

C Gaillardin, P Fournier, G Sylvestre, H Heslot

Mutants of Saccharomycopsis lipolytica defective in lysine catabolism

C Gaillardin et al. J Bacteriol. 1976 Jan.

Abstract

Wild-type strains of Saccharomycopsis lipolytica are able to use lysine as a carbon or a nitrogen source, but not as a unique source for both. Mutants were selected that could not use lysine either as a nitrogen or as a carbon source. Some of them, however, utilized N-6-acetyllysine or 5-aminovaleric acid. Many of the mutants appeared to be blocked in both utilizations, suggesting a unique pathway for lysine degradation (either as a carbon or as a nitrogen source). Genetic characterization of these mutants was achieved by complementation and recombination tests.

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