Comparative Study
[Role of adjuvant chemotherapy in the treatment of medulloblastoma in children]
[Article in
Russian]
Affiliations
- PMID: 12455354
Item in Clipboard
Comparative Study
[Role of adjuvant chemotherapy in the treatment of medulloblastoma in children]
[Article in
Russian]
Vopr Onkol.
2002.
Abstract
A retrospective review was carried out to evaluate the results of treatment (1989-1998) of 81 children, aged under 15, with primary medulloblastoma. Thirty-three patients received surgery and postoperative craniospinal radiotherapy; 48--adjuvant chemotherapy (VCR 1.5 mg/m2, i.v., 1 day; CCNU 75 mg/m2, per os, 1 day; cisplatin 80 mg/m2 or carboplatin 400 mg/m2, i.v., 1 day). Overall 9-year survival was 37 +/- 0.8%. This index in the adjuvant chemotherapy group was 59 +/- 0.8%, without chemotherapy--22 +/- 0.8%.
Similar articles
-
Treatment of patients of high-risk group of medulloblastoma with the adjuvant lomustine, cisplatin, and vincristine chemotherapy.Medicina (Kaunas). 2005;41(12):1026-34. Medicina (Kaunas). 2005. PMID: 16401959
-
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.J Clin Oncol. 2006 Sep 1;24(25):4202-8. doi: 10.1200/JCO.2006.06.4980. J Clin Oncol. 2006. PMID: 16943538 Clinical Trial.
-
Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy.J Neurosurg. 1994 Nov;81(5):690-8. doi: 10.3171/jns.1994.81.5.0690. J Neurosurg. 1994. PMID: 7931615 Clinical Trial.
-
Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa.Ann Neurol. 1990 Dec;28(6):823-8. doi: 10.1002/ana.410280615. Ann Neurol. 1990. PMID: 2178331 Review.
-
Radiotherapy for medulloblastoma in children: a perspective on current international clinical research efforts.Med Pediatr Oncol. 2002 Aug;39(2):99-108. doi: 10.1002/mpo.10116. Med Pediatr Oncol. 2002. PMID: 12116057 Review.