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Review
. 2002 Sep;84(9):841-8.
doi: 10.1016/s0300-9084(02)01459-1.

Developments in RNA chemistry, a personal view

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Review

Developments in RNA chemistry, a personal view

F Eckstein. Biochimie. 2002 Sep.

Abstract

This review describes some of the contributions of chemistry to the RNA field with a personal bias towards the phosphorothioate modification and the derivatives at the ribose 2'-position. The usefulness of these modifications is discussed and documented with some examples.

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