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Review
. 2002 Dec;107(4):387-93.
doi: 10.1046/j.1365-2567.2002.01545.x.

Immunomodulatory action of intravenous immunoglobulin

W A C Sewell  1 , S Jolles
Affiliations
Review

Immunomodulatory action of intravenous immunoglobulin

W A C Sewell et al. Immunology. 2002 Dec.
No abstract available

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Figures

Figure 1
Figure 1. Immunomodulatory actions of intravenous immunoglobulin. Intravenous immunoglobulin (IVIg) may for the purposes of understanding be thought of as four separate components: (1) actions mediated by the variable regions F(ab′)2, (2) actions of Fc on a range of Fc receptors (FcR), (3) actions mediated by complement binding within the Fc fragment, and (4) immunomodulatory substances other than antibody in the IVIg preparations. It should be remembered that not all of the potential mechanisms of action fit perfectly into the groupings and that several mechanisms may act concurrently. (TCR, T-cell receptor; ADCC, antibody-dependent cellular cytotoxicity).
See this image and copyright information in PMC

References

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