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Case Reports
. 2002 Dec;55(12):967-9.
doi: 10.1136/jcp.55.12.967.

Metastatic rectal adenocarcinoma to the liver associated with focal nodular hyperplasia

P J Nisar  1 , A M Zaitoun, A Damera, Z Hodi, G M Tierney, I J Beckingham
Affiliations
Case Reports

Metastatic rectal adenocarcinoma to the liver associated with focal nodular hyperplasia

P J Nisar et al. J Clin Pathol. 2002 Dec.

Abstract

A 45-year-old female patient underwent right hemihepatectomy for metastatic rectal adenocarcinoma. Preoperative imaging demonstrated an area of focal nodular hyperplasia (FNH) in segment VIII and metastatic carcinoma in segment VI of the liver. Gross and microscopic examination of the former lesion showed features typical of FNH with an intralesional metastatic adenocarcinoma. To the best of our knowledge, this is the first reported case of metastatic adenocarcinoma located within a lesion of FNH. The possibility of a pathogenetic association behind this occurrence is discussed.

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Figures

Figure 1
Figure 1
(A) Section of liver showing lesion A. Focal nodular hyperplasia almost completely surrounding a solid white nodule of metastatic carcinoma. (B) Focal nodular hyperplasia showing steatosis; haematoxylin and eosin stain; original magnification, ×4.
Figure 2
Figure 2
(A) Metastatic carcinoma in the right lower corner surrounded by focal nodular hyperplasia. (B) Multiple hamartomas and background liver showing steatosis. Haematoxylin and eosin stain; original magnification, ×4.
See this image and copyright information in PMC

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