Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2002 Dec 10;99(25):15855-7.
doi: 10.1073/pnas.262672799. Epub 2002 Dec 2.

Mitotic chromosome scaffold structure: new approaches to an old controversy

Andrew S Belmont  1
Affiliations
Comment

Mitotic chromosome scaffold structure: new approaches to an old controversy

Andrew S Belmont. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Figures

Fig 1.
Fig 1.
Loss of chromosome integrity by nuclease treatment alone is demonstrated by a chromosome micromanipulation experiment (5). Native chromosome (Before) loses elasticity after brief nuclease digestion (After). Stretching this partially digested chromosome leads to thin fiber extensions (0 sec), which are digested and then severed by further nuclease treatment.
See this image and copyright information in PMC

Comment on

References

    1. Li G., Sudlow, G. & Belmont, A. S. (1998) J. Cell Biol. 140, 975-989. - PMC - PubMed
    1. Belmont A. S. (1997) in Genome Structure and Function, ed. Nicolini, C. (Kluwer Academic, Dordrecht, The Netherlands), pp. 261–276.
    1. Tavormina P. A., Come, M. G., Hudson, J. R., Mo, Y. Y., Beck, W. T. & Gorbsky, G. J. (2002) J. Cell Biol. 158, 23-29. - PMC - PubMed
    1. Christensen M. O., Larsen, M. K., Barthelmes, H. U., Hock, R., Andersen, C. L., Kjeldsen, E., Knudsen, B. R., Westergaard, O., Boege, F. & Mielke, C. (2002) J. Cell Biol. 157, 31-44. - PMC - PubMed
    1. Poirier M. G. & Marko, J. F. (2002) Proc. Natl. Acad. Sci. USA 99, 15393-15397. - PMC - PubMed

MeSH terms

LinkOut - more resources