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. 2002 Dec;141(6):830-2.
doi: 10.1067/mpd.2002.129849.

Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide

Lisa K Kelly  1 , Nicolas F m Porta, Denise M Goodman, Christopher L Carroll, Robin H Steinhorn
Affiliations

Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide

Lisa K Kelly et al. J Pediatr. 2002 Dec.

Abstract

We report the use of inhaled prostacyclin (PGI(2)) in 4 neonates with persistent pulmonary hypertension and hypoxemia refractory to inhaled nitric oxide. Oxygenation rapidly improved after inhalation of PGI(2) in all infants. The condition of one infant subsequently deteriorated, and alveolar capillary dysplasia was found at autopsy. The surviving infants were discharged with normal oxygen saturations in room air.

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