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Review
. 2002 Nov-Dec;20(6 Suppl 28):S43-9.

Genetics of ankylosing spondylitis

M A Brown  1 , B P Wordsworth, J D Reveille
Affiliations
  • PMID: 12463446
Review

Genetics of ankylosing spondylitis

M A Brown et al. Clin Exp Rheumatol. 2002 Nov-Dec.

Abstract

Ankylosing spondylitis is a common inflammatory rheumatic disease. Both susceptibility to and clinical manifestations of the disease are highly heritable. Although some genes, notably HLA-B27, have been implicated in susceptibility to the disease, the genetics of the condition are complex and many more genes involved in the condition await discovery.

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