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. 2002 Dec;48(6):1011-20.
doi: 10.1002/mrm.10303.

Application of sensitivity-encoded echo-planar imaging for blood oxygen level-dependent functional brain imaging

Jacco A de Zwart  1 , Peter van Gelderen, Peter Kellman, Jeff H Duyn
Affiliations

Application of sensitivity-encoded echo-planar imaging for blood oxygen level-dependent functional brain imaging

Jacco A de Zwart et al. Magn Reson Med. 2002 Dec.

Abstract

The benefits of sensitivity-encoded (SENSE) echo-planar imaging (EPI) for functional MRI (fMRI) based on blood oxygen level-dependent (BOLD) contrast were quantitatively investigated at 1.5 T. For experiments with 3.4 x 3.4 x 4.0 mm(3) resolution, SENSE allowed the single-shot EPI image acquisition duration to be shortened from 24.1 to 12.4 ms, resulting in a reduced sensitivity to geometric distortions and T(*)(2) blurring. Finger-tapping fMRI experiments, performed on eight normal volunteers, showed an overall 18% loss in t-score in the activated area, which was substantially smaller than expected based on the image signal-to-noise ratio (SNR) and g-factor, but similar to the loss predicted by a model that takes physiologic noise into account.

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