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. 2002 Dec;10(12):1605-6.
doi: 10.1016/s0969-2126(02)00916-4.

RORalpha: an orphan nuclear receptor on a high-cholesterol diet

Free article

RORalpha: an orphan nuclear receptor on a high-cholesterol diet

Timothy M Willson. Structure. 2002 Dec.
Free article

Abstract

A high-resolution X-ray crystal structure of the retinoic acid receptor-related orphan receptor (RORalpha; NR1F1), which reveals a molecule of cholesterol within the ligand binding pocket, is a breakthrough in functional analysis of this orphan nuclear receptor.

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